The Health Canada’s revised in-commerce list (R-ICL) of chemicals used in food, drugs, and cosmetics no longer includes 602 substances that are not commercially active. These substances are therefore not subject to notification under the Food and drug Act (F&DA).
The R-ICL is a list of substances used in products introduced into commerce between 1 January 1987 and 13 September 2001. Substances listed under the New Substance Notification Regulation (NSNR) are not subject to notification requirements for F&DA-related uses.
As proposed in October, the government aimed to remove 544 substances produced or imported in quantities less than 100 kilograms yearly. It also aimed to delist 125 pharmaceutical ingredients that were discontinued or never marketed.
In an announcement on 18 February, the government said that it was removing all 125 pharmaceutical ingredients and all 477 substances below the 100kg annual threshold.
67 chemicals were not removed at this time, according to Health Canada, "because they were identified as potentially having commercial activity in Canada." However, removed substances can re-enter the Canadian market through the NSNR, which come under the Canadian Environmental Protection Act, 1999 (CEPA).
Global Product Compliance (GPC) specializes in Global Regulatory Compliance Solutions across sectors
globally. SSS Europe, a familiar name in chemical regulatory and compliance services now formally belongs
under the umbrella of GPC Holding Sweden.
Since 2008, we have emerged as one of the leading names among Global Regulatory Compliance Service Providers with Representation services in Europe, Asia and Middle East for respective chemical regulations.