GHS Report

Drug discovery services

We offer assistance for drug discovery and development action by orchestrating and executing a range of Developmental and Screening assays. These assays assess the impact of the new drug candidate on cellular, molecular, and biochemical levels, forming essential elements of the drug discovery process.

This is a crucial stage in the drug development process as it decreases the likelihood of post-marketing drug recalls by thoroughly assessing the drug candidates in the early phases. This wiss significantly cutting down the expenses of introducing a new drug to the market.
  • Buffer solubility
  • LogD7.4
  • pH stability in buffer & simulated body fluids
  • Plasma stability
  • Caco-2
  • Plasma & tissue extracts
  • Clint in liver microsome & Hepatocytes
  • Major human isoforms 3A4, 2D6 and 2C9
  • Bioavailability studies (IV/PO routes)
    • Serial sampling mice PK
    • Plasma/Brain distribution
    • Chemical-treated models for POC
    • PK parameters using WinNonlin
  • Screening of vehicles and excipients for a soluble parenteral formulation
  • HPLC based dose confirmation
  • LC-MS/MS based bioanalysis
  • Multiple sample extraction procedures

In Vivo Pharmacology
Provides valuable insights into the potential effectiveness of the compound in addressing the targeted disease area. We can assist you by creating tailored models for conducting tests and evaluations.
  • Obese mice model
  • STZ-induced diabetes in rat
  • Oral glucose tolerance test (OGTT) in rat
  • LPS-induced septicemia in mice
  • Carrageenan induced paw edema model in rat & mice
  • Xenograft models in nude mice (breast cancer and pancreatic cancer)
  • Syngenic models
  • Anticancer screening in 3D spheroids
  • Rodent exercise model for muscle building & endurance
  • Intra-Ocular Pressure model in rat
  • Colonization of intestine by probiotics in mice
  • Glucose and Cholesterol lowering
  • Probiotics in Wellness
  • Intra Ocular Pressure (IOP) &
  • Glaucoma
  • Anti-obesity/Weight gain reduction
  • Energy enhancers (AMPK pathway)
  • Thigh infection model in mice
  • Bacterecemia (sepsis)
  • Lung infection in mice
  • Growth inhibitory effect of essential oils
  • Immune modulation / stimulation model in mice

Cell & Microbiology
Our well-equipped microbiology laboratories provide a range of assays and screening options tailored to cellular and microbial research needs.